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Bring along 1 or 2 dedicated caregivers or leave her home with 1 or 2 dedicated caregivers. (The caregivers work opposite shifts.)
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Dad took Mom on a number of cruises when she had early Alzheimers.

Mom wanted to do some of the excursions. Dad would take Mom to the excursion leader. He would tell the excursion leader that Mom had early Alzheimers. Dad tipped the excursion leader generously in advance and
told him/her to make sure to bring his wife back. Mom went on excursions
and Dad stayed on the ship.
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On Dad's last cruise he decided he decided he needed a respite cruise so he would get a break from Mom. He picked a 3 week cruise out of Baltimore.

Dad went on the cruise.

I (daughter) stayed at the house with Mom and caregivers for the 3 weeks while Dad was gone on the cruise.

Consider giving yourself a break.
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How bad is her dementia? My husband and I are flying internationally for 5 weeks. I made all the arrangements. I am giving us breaks between segments so that he can rest. I will do all the driving, even though he thinks he can and should. He is a little apprehensive, but we are going to visit family and I have brought everyone up to date on how he is in his progression. He has some good days when he is 100% with it, but that means he is aware of his deficiencies and appreciates that I manage everything. Then he has days when he is different and hasn't a clue how to do what he is supposed to do. If your wife is in this stage of dementia, very careful planning can make it a good trip for both of you.
1. Make sure you get the relaxation you need. If you are exhausted and frustrated you will both be miserable.
2. Make sure whatever you do is comfortable and comforting. A lot of people and new things is never a good idea with dementia. They can get overstimulated easily.
3. Consider a trip to visit family and friends that you both hold dear but haven't seen recently. Plan some nice outings in calm, comfortable places. If music calms her take in a concert. If she likes arts and crafts do a paint-your-own-picture day. 4. Don't plan too many events per day.
5. If taking a car trip plan on stopping at minimum every 2 hours. Make this more than just a restroom stop, and make sure there is something to do or see that is pleasant.
6. Keep your plans flexible enough in case you need to go home early.
7. Bring extra personal supplies and medications in case things are lost in transit.
8. Bring her own pillow, to make it easier to sleep in unfamiliar surroundings. The feel and smell will be more restful.
9. If you took a special trip years ago, consider going again "for old times sake" and to relive wonderful memories. (Don't get upset or depressed if she doesn't remember clearly what you remember.)
10 Take LOTS of pictures, especially with her in them. This will help her later to try to recall the good time you had together.
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